- Product Name
- CasNo
- MF
- MW
- Content
- Appearance
- Packing
- Apply
- Bosutinib Monohydrate
- 918639-08-4
- C26H31Cl2N5O4
- 548.46144
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Crystallization of bosutinib from a wide...
This invention is directed to a crystall...
bosutinib
bosutinib monohydrate
| Conditions | Yield |
|---|---|
|
In
water;
at 80 ℃;
for 0.0833333h;
|
|
|
bosutinib;
In
water; isopropyl alcohol;
at 75 ℃;
In
water;
at 95 ℃;
for 5h;
|
|
|
In
water; isopropyl alcohol;
Heating / reflux;
|
4-((2,4-dichloro-5-methoxyphenyl)-amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)-propoxy)-3-quinoline-carbonitrile isopropanol solvate
bosutinib monohydrate
| Conditions | Yield |
|---|---|
|
In
water;
at 95 ℃;
for 3 - 24h;
Product distribution / selectivity;
|
bosutinib
4-((2,4-dichloro-5-methoxyphenyl)-amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)-propoxy)-3-quinoline-carbonitrile isopropanol solvate
4-((2,4-dichloro-5-methoxyphenyl)-amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)-propoxy)-3-quinoline-carbonitrile methanol solvate