- Product Name
- CasNo
- MF
- MW
- Content
- Appearance
- Packing
- Apply
- Estradiol
- 50-28-2
- C<sub>18</sub>H<sub>24</sub>O<sub>2</sub>
- 272.387
- white crystalline powder
Quality products make an important contribution to long-term revenue and profitability. Manufacturer supplie good quality Estradiol 50-28-2 with stock
Estradiol USP (Estrace) is used to treat Breast cancer; prostatic carcinoma.
Androstenedione
estradiol
Estrone
testosterone
Stanolone
Etiocholanolone
cis-androsterone
| Conditions | Yield |
|---|---|
|
With
carcinoma; gynecomastia; mammary dysplasia;
at 37 ℃;
for 1.5h;
Product distribution;
cofactors under 95percent O2: 5percent CO2, <3H>labeled study;
|
17β-estradiol 3'-(saccharinylmethyl) ether
formaldehyd
estradiol
saccharin
| Conditions | Yield |
|---|---|
|
With
phosphate buffer; water;
In
methanol;
at 37 ℃;
Rate constant;
various pH-values (4.98-7.98); half-life; other media, other temperature;
|
The CAS number of β-ESTRADIOL is 50-28-2.
More information of β-ESTRADIOL 50-28-2 are:
|
CAS Number |
50-28-2 |
|
Density |
1.17 g/cm3 |
|
Melting Point |
178-179 °C(lit.) |
|
Boiling Point |
445.917 °C at 760 mmHg |
|
Flash Point |
209.634 °C |
|
Vapor Pressure |
9.82E-09mmHg at 25°C |
|
Refractive Index |
80.4 ° (C=1, Dioxane) |
|
HS CODE |
29372390 |
|
PSA |
40.46000 |
|
LogP |
3.60920 |
|
Pka |
pKa 10.71±0.02(H2O(0.1% p-dioxane) t=25±0.1 I=0.03(KCl))(Approximate) |
Synonyms for β-ESTRADIOL 50-28-2:Estra-1,3,5(10)-triene-3,17-diol, (17b)-;Estra-1,3,5(10)-triene-3,17b-diol;Estrace;Estraderm;Estraderm MX;Estraldine;Estrapatch;Estreva;Estroclim;Estroclim 50;Estrogel HBF;Estropause;Evorel;FemSeven;Femogen;Follicyclin;Gelestra;Ginosedol;Gynoestryl;Macrodiol;Menorest;Menostar;Nordicol;Oestergon;Oestradiol;Oestrogel;Ovastevol;Ovocylin;Primofol;Profoliol;Dihydromenformon;Diogyn;Divigel;Encore;Epiestriol 50;Progynon;Progynon DH;Sandrena 1;Systen;Theelin, dihydro-;
The chemical formula of β-ESTRADIOL is C18H24O2 which containing 18 Carbon atoms,24 Hydrogen atoms and 2 Oxygen atoms,and the molecular weight of β-ESTRADIOL is 272.387.
β-Estradiol is an endogenous estrogenic hormone receptor (ER) agonist (Ki values are 0.12 and 0.13 nM for ERα and ERβ respectively). Also high affinity ligand at membrane estrogen GPR30 receptors. β-Estradiol is an activator of PI 3-kinase.Estradiol (17β-estradiol, β-Estradiol, E2, 17β-Oestradiol) is a human sex hormone and steroid, and the primary female sex hormone. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway.
InChI:InChI=1/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m0/s1
Relevant articles related to β-ESTRADIOL:
|
Article |
Source |
|
- |
MacCorquodale,Thayer,Doisy , p. 435,438 (1936) |
|
Substrate specificity of the placental microsomal aromatase |
Gibb,Lavoie , p. 507 - 519 (1980) |
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