- Product Name
- CasNo
- MF
- MW
- Content
- Appearance
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- Apply
- Polymyxin B Sulfate
- 1405-20-5
- C<sub>56</sub>H<sub>98</sub>N<sub>16</sub>O<sub>13</sub><sup>.</sup>H<sub>2</sub>SO<sub>4</sub>
- 1301.56
- White crystalline powder
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Polymyxin B sulfate is White crystalline powder, while it's Molecular Formula is C56H98N16O13.H2SO4. Polymyxin B sulfate is used as topical antibiotic agent, often used in combination with neomycin; products include ointments, creams, eye, and ear drops.
The CAS number of Polymyxin B sulfate is 1405-20-5.
More information of Polymyxin B sulfate 1405-20-5 are:
Synonyms |
Campho-Phenique Antibiotic Plus Pain Relief Ointment;Ophthocort;Neosporin Plus;Dexacidin;Neobacimyx (Veterinary);Polymixin B sulfate (JP14);Aerosporin (TN);Poly-Pred;Drotic;Pediotic Suspension;Statrol;2-[(4-amino-2-formamido-butanoyl)amino]-N-[3-amino-1-[[6,9,18-tris(2-aminoethyl)-15-benzyl-3-(2-hydroxyethyl)-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]carbamoyl]propyl]-4-hydroxy-butanamide; sulfuric acid;Neosporin;Aerosporin;Chloromyxin;Otocort;Mastimyxin; |
CAS Number |
1405-20-5 |
Molecular Formula |
C56H98N16O13.H2SO4 |
Molecular Weight |
1301.56 |
Melting Point |
217-220°C (dec.) |
Boiling Point |
1651ºC at 760 mmHg |
Flash Point |
952.3ºC |
HS CODE |
2941 90 00 |
PSA |
573.64000 |
LogP |
2.54990 |
Pka |
pKa 8.9 (Uncertain) |
The polymyxins are cationic peptides originally isolated from B. polymyxa. They bind and kill Gram-negative bacteria. The B series of polymyxins consist of a cyclic heptapeptide and a tripeptide side chain acylated at the amino terminus by a fatty acid. Polymyxin B (sulfate) is a mixture of at least four closely related components, polymyxin B1 to B4, with polymyxin B1 and B2 being the two major components. Polymyxin B (sulfate) has rapid in vitro bactericidal activity against major multidrug-resistant Gram-negative bacteria, such as P. aeruginosa, A. baumannii, and K. pneumoniae.
InChI:InChI=1/C48H82N16O13.H2O4S/c1-27(2)24-37-47(76)59-32(11-19-52)41(70)56-31(10-18-51)43(72)61-35(14-22-65)39(68)54-21-13-34(45(74)57-33(12-20-53)44(73)64-38(48(77)63-37)25-28-6-4-3-5-7-28)60-42(71)30(9-17-50)58-46(75)36(15-23-66)62-40(69)29(8-16-49)55-26-67;1-5(2,3)4/h3-7,26-27,29-38,65-66H,8-25,49-53H2,1-2H3,(H,54,68)(H,55,67)(H,56,70)(H,57,74)(H,58,75)(H,59,76)(H,60,71)(H,61,72)(H,62,69)(H,63,77)(H,64,73);(H2,1,2,3,4)
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