- Product Name
- CasNo
- MF
- MW
- Content
- Appearance
- Packing
- Apply
- Andarine S4
- 401900-40-1
- C<sub>19</sub>H<sub>18</sub>F<sub>3</sub>N<sub>3</sub>O<sub>6</sub>
- 441.364
- Pale yellow solid
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It is a potent and tissue-selective androgen receptor modulator (SARM)
4-acetaminophenol
![N-[4-nitro-3-(trifluoromethyl)phenyl]-(2R)-3-bromo-2-hydroxy-2-methylpropanamide](/upload/2025/10/53c41ec4-ba5a-4add-b390-54b6f6343bcb.png)
N-[4-nitro-3-(trifluoromethyl)phenyl]-(2R)-3-bromo-2-hydroxy-2-methylpropanamide
Ostarine
| Conditions | Yield |
|---|---|
|
With
potassium carbonate;
benzyltri(n-butyl)ammonium chloride;
In
butanone;
Heating / reflux;
|
86% |
|
With
potassium carbonate;
benzyltri(n-butyl)ammonium chloride;
In
butanone;
Heating / reflux;
|
86% |
|
With
potassium carbonate;
benzyltri(n-butyl)ammonium chloride;
In
butanone;
Heating / reflux;
|
86% |
|
With
potassium carbonate;
benzyltri(n-butyl)ammonium chloride;
In
butanone;
Heating / reflux;
|
86% |
|
With
benzyltri(n-butyl)ammonium chloride; potassium carbonate;
In
isopropyl alcohol;
for 4h;
Inert atmosphere;
Reflux;
|
77.8% |
|
With
benzyltri(n-butyl)ammonium chloride; potassium carbonate;
In
butanone;
for 24h;
Heating;
|
37% |
|
With
caesium carbonate;
In
tetrahydrofuran;
for 8h;
Inert atmosphere;
Reflux;
|
4-acetaminophenol
![(S)-(-)-3-bromo-2-hydroxy-2-methyl-N-[(4-nitro-3-trifluoromethyl)phenyl]propanamide](/upload/2025/10/641b3a79-d538-449a-9fec-47e0a6c9f220.png)
(S)-(-)-3-bromo-2-hydroxy-2-methyl-N-[(4-nitro-3-trifluoromethyl)phenyl]propanamide
![(2R)-3-(4-acetamidophenoxy)-N-[(4-nitro-3-(trifluoromethyl)phenyl)]-2-hydroxy-2-methylpropanamide](/upload/2025/10/6662fce0-ecfb-4edc-9f7d-bdbc16535130.png)
(2R)-3-(4-acetamidophenoxy)-N-[(4-nitro-3-(trifluoromethyl)phenyl)]-2-hydroxy-2-methylpropanamide
| Conditions | Yield |
|---|---|
|
With
benzyltri(n-butyl)ammonium chloride; potassium carbonate;
In
isopropyl alcohol;
for 4h;
Inert atmosphere;
Reflux;
|
79.3% |
The CAS number of Andarine is 401900-40-1.
More information of Andarine 401900-40-1 are:
|
CAS Number |
401900-40-1 |
|
Density |
1.472 g/cm3 |
|
Melting Point |
70-74 °C |
|
Boiling Point |
698.735 °C at 760 mmHg |
|
Flash Point |
376.381 °C |
|
Vapor Pressure |
0mmHg at 25°C |
|
Refractive Index |
1.605 |
|
PSA |
133.48000 |
|
LogP |
4.00970 |
|
Pka |
12.13±0.29(Predicted) |
Synonyms for Andarine 401900-40-1:N-[4-Nitro-3-(trifluoromethyl)phenyl]-(2S)-3-[4-(acetylamino)phenoxy]-2-hydroxy-2-methylpropanamide;
The chemical formula of Andarine is C19H18F3N3O6 which containing 19 Carbon atoms,18 Hydrogen atoms,3 Fluorine atoms,3 Nitrogen atoms and 6 Oxygen atoms,and the molecular weight of Andarine is 441.364.
Andarine (S-4) is the arylpropionamide-derived compound [S-3-(4-acetylamino-phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide] first described by Yin et al. to be a selective androgen receptor modulator (SARM). Andarine (S-4) was shown by in vitro and in vivo studies to be an effective anabolic agonist, without side-effects often associated with anabolic-androgenic steroids, relating principally to substrate affinity for 5α-reductase to produce DHT in the prostate. Unfortunately the benefits that SARMs such as andarine (S-4) may provide to clinical medicine have the potential for misuse in sports where athletes and/or their handlers may seek to gain unfair advantage with the assumption that these compounds are undetectable by anti-doping laboratories. SARMs are therefore prohibited for use by the International Federation of Horseracing Authorities and the World Anti-Doping Agency (WADA).
InChI:InChI=1/C19H18F3N3O6/c1-11(26)23-12-3-6-14(7-4-12)31-10-18(2,28)17(27)24-13-5-8-16(25(29)30)15(9-13)19(20,21)22/h3-9,28H,10H2,1-2H3,(H,23,26)(H,24,27)/t18-/m1/s1
Relevant articles related to Andarine:
|
Article |
Source |
|
METHODS OF TREATING UROLOGICAL DISORDERS USING SARMs |
- Paragraph 0424-0425, (2016/05/10) |
|
Compositions comprising 5-alpha reductase inhibitors, and SARMs and methods of use thereof |
- Page/Page column 23, (2010/11/24) |
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