- Product Name
- CasNo
- MF
- MW
- Content
- Appearance
- Packing
- Apply
- Methylprednisolone
- 83-43-2
- C<sub>22</sub>H<sub>30</sub>O<sub>5</sub>
- 374.477
- White to off-white crystalline powder
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Methylprednisolone is White to off-white crystalline powder, while it's Molecular Formula is C22H30O5. A glucocorticoid
The CAS number of Methylprednisolone is 83-43-2.
More information of Methylprednisolone 83-43-2 are:
|
Synonyms |
Pregna-1,4-diene-3,20-dione,11b,17,21-trihydroxy-6a-methyl- (7CI,8CI);11b,17,21-Trihydroxy-6a-methylpregna-1,4-diene-3,20-dione;6a-Methyl-11b,17a,21b-trihydroxy-1,4-pregnadiene-3,20-dione;6a-Methylprednisolone;Besonia;Duralone;M-Prednisol;Medorol;Medralone;Medrol;Metastab;Metilbetasone;Metrisone;NSC 19987;Prednol;Promacortine;Suprametil;Urbason;Urbasone;Wyacort;Methylphenisolone; |
|
CAS Number |
83-43-2 |
|
Molecular Formula |
C22H30O5 |
|
Molecular Weight |
374.477 |
|
Density |
1.28 g/cm3 |
|
Melting Point |
228-237 °C (dec.) |
|
Boiling Point |
571.8 °C at 760 mmHg |
|
Flash Point |
313.7 °C |
|
HS CODE |
2937290000 |
|
PSA |
94.83000 |
|
LogP |
1.80360 |
|
Pka |
12.46±0.70(Predicted) |
Methylprednisolone is a synthetic glucocorticoid, a type of corticosteroid hormone, that exhibits potent anti-inflammatory and immunosuppressive properties. It is structurally similar to the naturally occurring hormone cortisol and is used to treat a wide range of conditions characterized by inflammation, immune system disorders, and other medical issues.
Used in Pharmaceutical Industry:
Methylprednisolone is used as an anti-inflammatory and immunosuppressive drug for the treatment of various conditions, including rheumatoid arthritis, lupus, asthma, allergies, and skin conditions such as eczema and psoriasis. It helps to reduce inflammation, suppress the immune system, and alleviate symptoms associated with these conditions.
Used in Neurological Applications:
Methylprednisolone is used as a neuroprotective agent for the attenuation of apoptosis in oligodendrocytes after injury. Its neuroprotective properties make it a valuable treatment option for conditions involving damage to the nervous system, such as spinal cord injuries and multiple sclerosis.
Used in Emergency Medicine:
Methylprednisolone is used as a treatment for acute spinal cord injuries to reduce the severity of the injury and improve the chances of recovery. It is typically administered as part of a high-dose steroid protocol in the immediate aftermath of the injury to minimize inflammation and protect the nervous tissue.
Used in Organ Transplantation:
Methylprednisolone is used as an immunosuppressive agent in organ transplantation to prevent organ rejection and promote the acceptance of the transplanted organ by the recipient's immune system. It helps to suppress the immune response and reduce the risk of graft-versus-host disease.
InChI:InChI=1/C22H30O5/c1-12-8-14-15-5-7-22(27,18(26)11-23)21(15,3)10-17(25)19(14)20(2)6-4-13(24)9-16(12)20/h4,6,9,12,14-15,17,19,23,25,27H,5,7-8,10-11H2,1-3H3/t12-,14?,15?,17-,19?,20-,21-,22-/m0/s1
Articles related to Methylprednisolone:
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Article |
Source |
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Kinetics of drug release from a hyaluronan-steroid conjugate investigated by NMR spectroscopy |
Taglienti, Anna,Sequi, Paolo,Valentini, Massimiliano , p. 245 - 249 (2009) |
|
Method for reducing or preventing transplant rejection in the eye and intraocular implants for use therefor |
- , (2008/06/13) |
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