Manufacturer Sells Best Quality Trilostane 13647-35-3 with stock We supply high quality Trilostane (CAS 13647-35-3), in stock, factory directly supply to clients, lower prices, more competitiveness.

What is the Trilostane ?

Trilostane is tan crystals, while it's Molecular Formula is C₂₀H₂₇NO₃. Trilostane has been used to evaluate its capability to regulate the sex-dependent differences in the lipopolysaccharide (LPS)-induced inflammatory responses of astrocytes.

What is the CAS number for Trilostane ?

The CAS number of Trilostane is 13647-35-3.

More information of Trilostane 13647-35-3 are:

What is Trilostane (13647-35-3) used for?

3β-hydroxysteroid dehydrogenase (3β-HSD) type 1 and type 2 isoforms are key enzymes for the biosynthesis of all active steroid hormones. 3β-HSD1 (type I) is expressed in placenta and peripheral tissues including breast tumors, whereas 3β-HSD2 (type 2) is expressed in the adrenal gland, ovary, and testis. Trilostane is an inhibitor of the 3β-HSDs: 3β-HSD1 and 3β-HSD2 with Ki values of 0.10 and 1.60 μM, respectively. Trilsotane has been approved for use in the treatment of Cushing’s syndrome in dogs to reduce cortisol, aldosterone, and corticosterone levels. Because human 3β-HSD (type 1) is a critical enzyme in the conversion of DHEA to estradiol in breast tumors, trilostane is also of interest for the treatment of breast cancer in postmenopausal women.

InChI:InChI=1/C20H27NO3/c1-18-7-6-14-12(13(18)3-4-15(18)22)5-8-20-17(24-20)16(23)11(10-21)9-19(14,20)2/h12-15,17,22-23H,3-9H2,1-2H3/t12-,13-,14-,15-,17+,18-,19+,20+/m0/s1

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How to get the best price on Trilostane?

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